syndecan-4; SYND4; amphiglycan; Ryudocan core protein (SDC4)

Introduction

plasma membrane embedded proteoglycan core protein

Function

• cell surface proteoglycan that bears heparan sulfate homodimer
• plasma membrane embedded proteoglycan core protein
• interacts with CDCP1, with GIPC PDZ domain & with NUDT16L1/SDOS (putative)
• interacts with SDCBP

Structure

belongs to the syndecan proteoglycan family

Compartment

plasma membrane

Expression

expressed in epithelial cells & fibroblasts

More general terms

• proteoglycan core protein
• plasma membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/P31431.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6385
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6385
• OMIM: https://mirror.omim.org/entry/600017