K+ voltage-gated channel subfamily KQT member 1; voltage-gated K+ channel subunit Kv7.1; IKs producing slow voltage-gated K+ channel subunit alpha KvLQT1; KQT-like 1 (KCNQ1, KCNA8, KCNA9, KVLQT1, KCNQ1OT1)

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Function

Structure

  • the segment S4 is probably the voltage-sensor & is characterized by a series of positively charged amino acids at every third position
  • belongs to the K+ channel family, KQT subfamily

Compartment

Alternative splicing

named isoforms=2 additional isoforms seem to exist; truncated isoform non-functional alone but modulatory when coexpressed with the full-length isoform 1

Expression

Pathology

More general terms

References

Database