voltage-gated K+ channel
Jump to navigation
Jump to search
Function
- establish resting membrane potential
- modulate frequency & duration of action potential in neurons & muscle cells
Structure
- four alpha subunits form a functional K+ channel
- beta subunits are accessory (modulatory)
More general terms
More specific terms
- K+ voltage-gated channel subfamily KQT member 1; voltage-gated K+ channel subunit Kv7.1; IKs producing slow voltage-gated K+ channel subunit alpha KvLQT1; KQT-like 1 (KCNQ1, KCNA8, KCNA9, KVLQT1, KCNQ1OT1)
- voltage-gated K+ A channel (K+ channel IA , ISA, IA, A type K+ channel)
Additional terms
References
- ↑ Kubo Y, Baldwin TJ, Jan YN, Jan LY. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature. 1993 Mar 11;362(6416):127-33. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7680768
- ↑ Martens JR, Kwak YG, Tamkun MM. Modulation of Kv channel alpha/beta subunit interactions. Trends Cardiovasc Med. 1999 Nov;9(8):253-8. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11094335
- ↑ Chen X and Johnston D Properties of single voltgage-dependent K+ channels in dendrites of CA1 pyramidal neurones of rat hippocampus. J Physiol 2004, 559:187 PMID: https://www.ncbi.nlm.nih.gov/pubmed/15218076