peptidyl-prolyl cis/trans isomerase (PPIase) or rotamase
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Classification
classified into 3 families:
- cyclophilins
- FK506 binding proteins
- parvulins (includes parvulins & pin1 protein)
Function
- accelerates the folding of proteins
- catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
More general terms
More specific terms
- immunophilins (includes cyclophilins & FK506 binding proteins)
- peptidyl-prolyl cis-trans isomerase A-like 4C; PPIase A-like 4C (PPIAL4C)
- peptidyl-prolyl cis-trans isomerase A-like 4D; PPIase A-like 4D (PPIAL4D)
- peptidyl-prolyl cis-trans isomerase A-like 4E; PPIase A-like 4E (PPIAL4E)
- peptidyl-prolyl cis-trans isomerase A-like 4F; PPIase A-like 4F (PPIAL4F)
- peptidyl-prolyl cis-trans isomerase A-like 4G; PPIase A-like 4G; peptidylprolyl cis-trans isomerase A-like 4 (PPIAL4G)
- peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1 (PIN1)
- peptidyl-prolyl cis-trans isomerase-like 1 (PPIase, rotamase, PPIL1, CYPL1, CGI-124, UNQ2425/PRO4984)
- peptidyl-prolyl cis-trans isomerase-like 4 (PPIase, Rotamase, cyclophilin-like protein PPIL4, PPIL4)
- peptidylprolyl cis-trans isomerase A-like 4B (PPIase A-like 4B, chromosome 1-amplified sequence 2, COAS-2, cyclophilin homolog overexpressed in liver cancer, PPIAL4B COAS2)
- peptidylprolyl isomerase domain and WD repeat-containing protein 1 (PPWD1, KIAA0073)
References
- ↑ Lu KP, Liou YC, Zhou XZ. Pinning down proline-directed phosphorylation signaling. Trends Cell Biol. 2002 Apr;12(4):164-72. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11978535
- ↑ Tai PK et al Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex. Science 256:1315 1992 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1376003