peptidyl-prolyl cis-trans isomerase A-like 4D; PPIase A-like 4D (PPIAL4D)

Function

• PPIases accelerate the folding of proteins
• catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (putative)

peptidylproline (omega=180) = peptidylproline (omega=0)

Structure

• belongs to the cyclophilin-type PPIase family, PPIase A subfamily
• contains 1 PPIase cyclophilin-type domain

Compartment

cytoplasm (putative)

Notes

• one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 1

More general terms

• peptidyl-prolyl cis/trans isomerase (PPIase) or rotamase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=645142
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=728945
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=730262
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:645142
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:728945
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:730262
• UniProt: http://www.uniprot.org/uniprot/F5H284.html