peptidylprolyl isomerase domain and WD repeat-containing protein 1 (PPWD1, KIAA0073)

Function

• component of spliceosome C complex
• putative peptidylprolyl isomerase
• accelerates the folding of proteins
• catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
• may be involved in pre-mRNA splicing

Structure

• belongs to the cyclophilin-type PPIase family, PPIL1 subfamily
• contains 1 PPIase cyclophilin-type domain
• contains 4 WD repeats

More general terms

• peptidyl-prolyl cis/trans isomerase (PPIase) or rotamase

Component of

• spliceosome C complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q96BP3.html