thrombin time (TT)

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Introduction

The assay is performed adding exogenous thrombin to citrated plasma & measuring the time to clot formation. Normal value:

  • time of control +/- 2 sec when control is 9-13 sec
  • time of control +/- 5 sec when control is 15-20 sec

Clinical significance

Increases

* may be associated with frequent or severe bleeding[3]

More general terms

More specific terms

Additional terms

Component of

References

  1. Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 726
  2. Guide to Clinical Laboratory Tests, 3rd ed, NW Teitz (ed) WB Saunders, 1995
  3. 3.0 3.1 Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 322
  4. Medical Knowledge Self Assessment Program (MKSAP) 16, 18. American College of Physicians, Philadelphia 2012, 2018.
  5. Panel of 12 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0030181.jsp
  6. Thrombin Time Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0030260.jsp
  7. Panel of 16 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0030268.jsp
  8. Panel of 16 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0000000.jsp