pyridoxal phosphate phosphatase; PLP phosphatase; chronophin (PDXP, CIN, PLP, PLPP)

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Function

pyridoxal-5'-phosphate + H2O = pyridoxal + phosphate

O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate

Cofactor: divalent ions. Mg+2 is the most effective

Inhibition:

Structure

Compartment

Expression

  • ubiquitous
  • highly expressed in all regions of the brain
  • lower expression in spinal cord
  • highly expressed in liver & testis
  • in fetus, weakly expressed in all organs except brain

More general terms

More specific terms

Additional terms

References

Database