protor-2; protein observed with Rictor-2 (PROTOR2, PRR5L)
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Function
- may be part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, & may modulate the phosphorylation of PKCA & regulate actin cytoskeleton organization
- may replace PROTOR1 in the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR & MAPKAP1
Structure
belongs to the PROTOR family
Alternative splicing
named isoforms=3