posterior uveitis (choroiditis)
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Introduction
Inflammation of the vitreous, retina or choroid. It is more likely than anterior uveitis to be associated with a systemic disorder.
Etiology
- sarcoidosis
- Behcet's syndrome
- Vogt-Koyanagi-Harada syndrome
- inflammatory bowel disease
- toxoplasmosis
- onchocerciasis
- cysticercosis
- coccidioidomycosis
- toxocariasis
- histoplasmosis
- Candida
- Pneumocystis carinii
- Cryptococcus
- Aspergillus
- Herpes
- Cytomegalovirus
- syphilis
- Lyme disease
- tuberculosis
- cat-scratch disease
- Whipple's disease
- brucellosis
- multiple sclerosis (in periphery of retina)
- pharmaceutical agents
Pathology
- may be associated with autoantibodies to UACA
- may be associated with autoantibodies to TRIB2
- iron-binding acute phase protein detected with variable frequency in serum of patients with posterior uveitis (non-specific)
Clinical manifestations
- ocular pain
- photophobia
- visual impairment
- red eye: scleral erythema
- vitreous inflammation & clouding
- floaters[3]
- clear cornea[4]
Laboratory
Management
- also see anterior uveitis
- topical steroids - prednisolone (Pred Forte)
- dilation of the pupil reduces pain & prevents formation of synechiae
- treat underlying disorder
- discontinue offending pharmaceutical agent(s)
- referral to an ophthalmologist[3]
More general terms
More specific terms
References
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 165
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- ↑ Jump up to: 3.0 3.1 3.2 Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
- ↑ Jump up to: 4.0 4.1 NEJM Knowledge+. Question of the Week. Aug 9, 2016 http://knowledgeplus.nejm.org/question-of-week/1519/