protein inhibitor of activated STAT (PIAS)
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Introduction
Originally identified as inhibitors of the STAT family of signal transducers & transcription factors.
It appears now the PIAS proteins function as E3-like ligases in protein sumoylation.
More general terms
More specific terms
- protein inhibitor of activated STAT1 (PIAS1, DEAH box binding protein 1, DDXBP1)
- E3 SUMO-protein ligase PIAS2; androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; Msx-interacting zinc finger protein; Miz1; PIAS-NY protein; protein inhibitor of activated STAT x; protein inhibitor of activated STAT2 (PIAS2,...
- E3 SUMO-protein ligase PIAS3; protein inhibitor of activated STAT protein 3 (PIAS3)
- E3 SUMO-protein ligase PIAS4; PIASy; protein inhibitor of activated STAT protein 4; protein inhibitor of activated STAT protein gamma; PIAS-gamma (PIAS4, PIASG)
References
- ↑ Scmidt D & Muller S PIAS/SUMO: new partners in transcriptional regulation. Cell Mol Life Sci. 2003 Dec;60(12):2561-74. PMID: https://www.ncbi.nlm.nih.gov/pubmed/14685683