magnesium citrate (citrate of magnesia)

Indications

• relief of constipation
• hypomagnesemia
• dyspepsia
• bowel preparation

Contraindications

pregnancy-category :value +

safety-in-lactation :value ?

Dosage

• 4 mL/kg PO up to 300 mL
• 4-8 oz once; may be repeated once

Liquid: 10 oz bottle.

Pharmacokinetics

• onset of bowel relief is in 3-6 hours
• elimination :route kidney)

Adverse effects

• repeated or frequent administration may cause
  • hypermagnesemia
  • electrolyte imbalance
  • dehydration

Mechanism of action

• saline laxative
• Mg+2 may stimulate release of cholecystokinin, which increases motor & sensory action in the GI tract

More general terms

• pharmaceutical magnesium
• laxative
• citrate (citric acid)

Additional terms

• calcium & magnesium citrate

Component of

• calcium & magnesium citrate
• dimethicone/magnesium citrate
• magnesium citrate/simethicone
• calcium lactate/glucose/magnesium citrate/potassium chloride/sodium chloride

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=24511
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=107785