inflammatory markers (iAGE)
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Clinical significance
- inflammatory markers ESR & CRP are used in evaluation of inflammatory diseases
- procalcitonin is use to assess inflammation associated with infection
- inflammatory marker chemokine CXCL9 upregulates multiple genes implicated in inflammation & is involved in cellular senescence, vascular aging & adverse cardiac remodeling[2]
More general terms
Additional terms
Components
- erythrocyte sedimentation rate (ESR)
- C-reactive protein (CRP) in serum/plasma
- procalcitonin in serum (Vidas Brahms PCT Assay)
- C-X-C motif chemokine 9; gamma-interferon-induced monokine; monokine induced by interferon-gamma; HuMIG; MIG; small-inducible cytokine B9 (CXCL9, CMK, MIG, SCYB9)
References
- ↑ ARUP Consult: Inflammatory Markers The Physician's Guide to Laboratory Test Selection & Interpretation. https://arupconsult.com/content/inflammatory-markers
- ↑ 2.0 2.1 Buck Institute for Research on Aging 'Clock' created to predict immunological health and chronic diseases of aging Research highlights the critical role of the immune system in the aging process. Science Daily. Science News. July 12, 2021 https://www.sciencedaily.com/releases/2021/07/210712122159.htm
Sayed N, Huang Y, Nguyen K et al An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging. Nature Aging 2021 Not indexed in PubMed https://www.nature.com/articles/s43587-021-00082-y