procalcitonin; contains: calcitonin, katacalcin; calcitonin carboxyl-terminal peptide; CCP; PDN-21 (CALCA, CALC1)

Function

• precursor to calcitonin
• precursor to katacalcin

Structure

belongs to the calcitonin family

Compartment

secreted

Alternative splicing

• named isoforms=3
• at least one isoform may be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay

Laboratory

• serum procalcitonin appears to be a marker of bacterial infection

More general terms

• calcitonin

Additional terms

• procalcitonin in serum (Vidas Brahms PCT Assay)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=796
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:796
• OMIM: https://mirror.omim.org/entry/114130
• UniProt: http://www.uniprot.org/uniprot/P01258.html