aldosterone in 24 hour urine
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Reference interval
- 5-19 ug/24 hours (13.9-52.7 nmol/24 hours)*
* 24 hour urine, assumes normal sodium intake
* cutoff for diagnosis of primary hyperaldosteronism is 12 ug/24 hours[3]
Increases
- primary hyperaldosteronism
- angiotensin
- corticotropin
- ethacrynic acid
- lithium carbonate
- loop diuretics: furosemide
- thiazide diuretics
- oral contraceptives (some)
Decreases
- aminoglutethimide
- clonidine
- deoxycorticosterone
- fludrocortisone
- glucocorticoids
- labetalol
- licorice
- heparin
- metyrapone
- propranol
Methods
- see aldosterone in serum/urine
Specimen
- urine 4 hours, refrigerate during collection
- add 50% acetic acid at completion of collection to adjust pH to 2-4
- store frozen
More general terms
More specific terms
Additional terms
Component of
References
- ↑ Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz ed, WB Saunders, Philadelphia, 1995
- ↑ Panel of 6 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0070480.jsp
- ↑ 3.0 3.1 Brown JM, Siddiqui M, Calhoun DA et al. The unrecognized prevalence of primary aldosteronism: A cross-sectional study. Ann Intern Med 2020 May 26; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32449886 https://www.acpjournals.org/doi/10.7326/M20-0065
Funder JW. Primary aldosteronism: At the tipping point. Ann Intern Med 2020 May 26; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32449882 https://www.acpjournals.org/doi/10.7326/M20-1758