colon cancer genotyping

Genetics

• associated genetic aberrations:
  • adenomatous polyposis coli (FAP) gene
  • mutated in colon carcinoma (MCC) tumor suppressor gene
  • deleted in colon carcinoma (DCC) tumor suppressor gene

Indications

• colorectal carcinoma

Specimen

• colon tissue
• whole blood (ACD or EDTA)
• store body fluid at 4 degrees C
• store tissue at -20 degrees C or below

More general terms

• genotyping (allele testing)

Additional terms

• adenocarcinoma of the colon &/or rectum
• APC gene mutation
• Deleted in Colon Carcinoma [DCC] tumor suppressor gene
• familial adenomatous polyposis [FAP] gene
• Mutated in Colon Carcinoma [MCC] tumor suppressor gene

Components

• APC gene mutation