Adrenocortical dysplasia protein homolog (POT1 & TIN2-interacting protein) (ACD PIP1 PTOP)

Function

• role of telomeric regulator as component of TRF1 complex controlling telomere length
• controls POT1 telomeric recruitement & telomere elongation by inhibition of telomerase activity
• may play a role in organogenesis
• forms heterodimers with POT1
• interacts with TINF2
• component of TRF1 complex

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

More general terms

• other protein

Additional terms

• adrenal cortex

Component of

• double-stranded telomeric DNA-binding TRF1 complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q96AP0.html