SCF(NIPA) E3 ligase complex

Function

• controls mitotic entry by mediating ubiquitination & subsequent degradation of cyclin B1 (CCNB1)

Structure

• subunits include: SKP1, RBX1, CUL1 & ZC3HC1

More general terms

• SCF-type E3 ligase complex

Additional terms

• E3 ubiquitin ligase; ubiquitin-ligating enzyme E3; N end-recognizing protein