methylene blue; methylthioninium chloride (Provablue, MTC)

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Indications

Dosage

Injection: 10 mg/mL (10 mL)

Adverse effects

Drug interactions

Mechanism of action

Clinical trials

* control group receiving methylthioninium chloride as an agent to dicolor urine in the placebo also showed cognitive improvement[7]

More general terms

Additional terms

Component of

References

  1. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  2. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  3. Department of Veterans Affairs, VA National Formulary
  4. 4.0 4.1 FDA Medwatch - 07/26/2011 Methylene Blue: Drug Safety Communication - Serious CNS Reactions Possible When Given to Patients Taking Certain Psychiatric Medications http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm265476.htm
  5. FDA MedWatch: 10/21/2011 Methylene Blue: Drug Safety Communication - Serious CNS Reactions Possible When Given to Patients Taking Certain Psychiatric Medications http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm265476.htm
  6. 6.0 6.1 Atalla AS, Palka J 12 Causes of Discolored Urine. Medscape. Nov 15, 2017 https://reference.medscape.com/slideshow/discolored-urine-6008332
  7. 7.0 7.1 7.2 7.3 Dotinga R Odd Twist in Phase 3 Alzheimer's Trial for Novel Tau Inhibitor. Medscape. December 1, 2022 https://www.medscape.com/viewarticle/984863

Database