adrenal steroid biosynthesis

Introduction

see figure

Biochemistry

• steroid biosynthesis 9 :enzyme multienzyme-complex
  • steroid-21-hydroxylase, cytochrome P450 reductase :substrate progesterone + O2 + NADPH :product deoxycorticosterone + NADP
• steroid biosynthesis 10 :enzyme multienzyme-complex
  • steroid-21-hydroxylase, cytochrome P450 reductase :substrate 17-hydroxyprogesterone + O2 + NADPH :product 11-deoxycortisol + NADP
• steroid biosynthesis 11 :enzyme multienzyme-complex
  • steroid-11-hydroxylase, adrenodoxin, adrenodoxin reductase :substrate deoxycorticosterone + O2 + NADPH :product corticosterone + NADP
• steroid biosynthesis 12 :enzyme multienzyme-complex
  • steroid-11-hydroxylase, adrenodoxin, adrenodoxin reductase :substrate 11_deoxycortisol + O2 + NADPH :product cortisol + NADP)
• steroid biosynthesis 13 :enzyme multienzyme-complex
  • steroid-11-hydroxylase, adrenodoxin, adrenodoxin reductase :substrate corticosterone + O2 + NADPH :product aldosterone + NADP

More general terms

• steroid biosynthesis

Additional terms

• adrenal cortex hormone; corticosteroid

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?