transglutaminase (protein-glutamine:amine gamma-glutamyltransferase)

Introduction

Catalyzes condensation of epsilon amino group of lysine with gamma-carboxyl group of glutamine residues. Glutamine may be used instead of lysine, i.e. factor XIIIa??? Stable intermolecular crosslinks form.

More general terms

• glutamyltransferase
• Ca+2 binding protein
• regulatory molecule

More specific terms

• coagulation factor XIIIa; transglutaminase
• transglutaminase 3-like (protein-glutamine gamma-glutamyltransferase 3-like, transglutaminase 6, TGM6)
• transglutaminase 7 or protein-glutamine gamma-glutamyltransferase Z
• transglutaminase-1, keratinocyte transglutaminase, epidermal transglutaminase, or transglutaminase-K
• transglutaminase-2 (tissue transglutaminase, tranglutaminase-C, TGM2)
• transglutaminase-3 (tranglutaminase-E, E3, TGM3)
• transglutaminase-4 [prostate] (fibrinoligase, prostate transglutaminase, TGP, prostate-specific transglutaminase, TGM4)
• transglutaminase-5 (TGM5, protein-glutamine gamma-glutamyltransferase X)