coagulation factor XIIIa; transglutaminase

Function

• fibrin stabilizing factor
• catalyzes condensation of epsilon amino group of lysine with gamma-carboxyl group of glutamate residues
• glutamine may be used instead of lysine
• cross-links fibrin & other proteins
• formed via cleavage by thrombin from factor XIII (Ca+2-dependent)

More general terms

• coagulation factor
• transglutaminase