transglutaminase-4 [prostate] (fibrinoligase, prostate transglutaminase, TGP, prostate-specific transglutaminase, TGM4)

Function

• associated with the mammalian reproductive process catalyzes the cross-linking of proteins & the conjugation of polyamines to specific proteins in the seminal tract

protein glutamine + alkylamine
               <-->
protein N(5)-alkylglutamine + NH3

Cofactor: binds 1 Ca+2 per subunit (putative)

Structure

• belongs to the transglutaminase superfamily transglutaminase family

Expression

prostate

More general terms

• transglutaminase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7047
• OMIM: https://mirror.omim.org/entry/600585
• UniProt: http://www.uniprot.org/uniprot/P49221.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7047