nucleosome remodeling & histone deacetylation (NuRD) complex

Function

• promotes transcriptional repression by histone deacetylation & nucleosome remodeling
• interacts with MTA1
• may interact with MBD3L1 & MBD3L2

Structure

• subunits:
  • HDAC core complex, MTA2, MBD2, MBD3, MTA1L1, CHD3 & CHD4

More general terms

• molecular complex