interferon-induced GTP-binding protein Mx1; myxovirus resistance protein 1; interferon-regulated resistance GTP-binding protein MxA; interferon-induced protein p78; IFI-78K (MX1)

Function

• may regulate the Ca+2 channel activity of TRPCs
• shows activity against influenza virus & VSV, a rhabdovirus
• interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 & TRPC7

Structure

• belongs to the dynamin family
• contains 1 GED domain

Compartment

cytoplasm

Expression

induced by interferons

More general terms

• guanine nucleotide regulatory protein (GNRP)
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P20591.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4599
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4599
• OMIM: https://mirror.omim.org/entry/147150