short transient receptor potential channel 1 (TrpC1, TRP-1 protein, transient receptor potential cation channel subfamily C member 1, TRP1)

Function

• forms a receptor-activated non-selective Ca+2 permeant cation channel
• linked to phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors (putative).
• activated by intracellular Ca+2 store depletion
• interacts with TRPC3, ITPR3

Structure

• contains 3 ANK repeats

Compartment

membrane

Alternative splicing

named isoforms=2

Expression

ubiquitous

More general terms

• transient receptor potential cation channel subfamily C (TRPC)
• transmembrane 6 protein

Database

• OMIM: https://mirror.omim.org/entry/602343
• UniProt: http://www.uniprot.org/uniprot/P48995.html