cleavage & polyadenylation specificity factor (CPSF) complex

Function

• mRNA 3'polyadenylation
• recognizes AAUAAA signal sequence.
• in concert with poly[A]polymerase, facilitates 3' polyadenylation of mRNA

Structure

• components include: CPSF1, CPSF2, CPSF3, CPSF4, FIP1L1

More general terms

• adenine phosphoribosyltransferase (APRT)
• multisubunit protein
• nuclear protein
• RNA-binding protein