cleavage & polyadenylation specificity factor subunit 2; cleavage & polyadenylation specificity factor 100 kD subunit; CPSF 100 kD subunit (CPSF2, CPSF100, KIAA1367)

Function

• component of the CPSF complex involded in pre-mRNA 3'-end formation
• involved in the histone 3'-end pre-mRNA processing
• interacts with CPSF3, CSTF2 & SYMPK

Structure

• belongs to the metallo-beta-lactamase superfamily RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily

Compartment

nucleus (putative)

More general terms

• protein subunit
• nuclear protein
• RNA-binding protein
• phosphoprotein

Component of

• cleavage & polyadenylation specificity factor (CPSF) complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=53981
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:53981
• OMIM: https://mirror.omim.org/entry/606028
• UniProt: http://www.uniprot.org/uniprot/Q9P2I0.html