plexin-A1; semaphorin receptor NOV (PLXNA1, NOV, PLXN1)

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Function

* class 3 semaphorins bind to a complex composed of a neuropilin & a plexin; the plexin modulates affinity of the complex for specific semaphorins

Structure

  • belongs to the plexin family
  • contains 4 IPT/TIG domains
  • contains 1 Sema domain

Compartment

membrane

Expression

expressed in fetal brain, lung, liver, kidney

More general terms

References

Database