semaphorin-3F; semaphorin IV; sema IV; sema III/F (SEMA3F)

Function

• may play a role in cell motility & cell adhesion

Structure

• belongs to the semaphorin family
• contains 1 Ig-like C2-type domain (immunoglobulin-like)
• contains 1 sema domain

Compartment

• secreted (putative)

Expression

• expressed abundantly but differentially in a variety of neural & nonneural tissues
• high expression in mammary gland, kidney, fetal brain, & lung
• lower expression in heart & liver
• detected as early as embryonic day 10

More general terms

• secreted protein
• glycoprotein
• semaphorin or semaphorin/collapsin family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6405
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6405
• OMIM: https://mirror.omim.org/entry/601124
• UniProt: http://www.uniprot.org/uniprot/Q13275.html