TRAF2 & NCK-interacting protein kinase (TNIK, KIAA0551)

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Function

Structure

Compartment

Alternative splicing

named isoforms=8

Expression

Pathology

  • a small molecule inhibitor of TNIK has antifibrotic properties across different organs[2]

More general terms

Additional terms

References

  1. UniProt http://www.uniprot.org/uniprot/Q9UKE5.html
  2. 2.0 2.1 Ren F, Aliper A, Chen J et al A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models. Nat Biotechnol 2024. March 8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38459338 https://www.nature.com/articles/s41587-024-02143-0

Database