vesicle-trafficking protein SEC22b; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1 (ERS24, ERS-24, SEC22B, SEC22L1)

Function

• v-SNARE
  • targeting & fusion of ER-derived transport vesicles with Golgi, &
  • targeting & fusion of Golgi-derived retrograde transport vesicles with the ER
• component of 2 distinct SNARE complexes consisting of
  • STX5, GOSR2/BOS1, BET1 and SEC22B or
  • STX18, USE1L, BNIP1/SEC20L
  • YKT6 can likely replace SEC22B in either complex

Compartment

endoplasmic reticulum-Golgi intermediate compartment

More general terms

• SNARE protein

Database

• OMIM: https://mirror.omim.org/entry/604029
• UniProt: http://www.uniprot.org/uniprot/O75396.html