ARF GTPase-activating protein GIT2; ARF GAP GIT2; G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2; cool-interacting tyrosine-phosphorylated protein 2; CAT-2; CAT2 (GIT2, KIAA0148)

Function

• GTPase-activating protein for the ADP ribosylation factor family
• interacts with TGFB1I1 (putative)
• interacts with G protein-coupled receptor kinases
• associates with paxillin
• also interacts with PIX exchange factors

Structure

• contains 3 ANK repeats
• contains 1 Arf-GAP domain

Alternative splicing

named isoforms=11

More general terms

• ADP-ribosylation factor GTPase activating protein (ARF-GAP)
• zinc finger protein
• receptor
• ankyrin repeat domain protein (ANKRD)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9815
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9815
• OMIM: https://mirror.omim.org/entry/608564
• UniProt: http://www.uniprot.org/uniprot/Q14161.html