integrin alpha-D/beta-2 (CD11d/CD18)

Function

• receptor for ICAM3 & VCAM1
• may play a role in phagocytosis
  • clearing lipoproteins from atherosclerotic plaques
  • phagocytosis of blood-borne pathogens, particulate matter, & senescent erythrocytes

Structure

• subunits: integrin alpha-D, integrin beta-2

Compartment

membrane

More general terms

• integrin