biliverdin reductase
Jump to navigation
Jump to search
Function
- reduces bilirubin to biliverdin in the catabolism of heme & in the biliverdin reductase cycle, a key antioxidant system in the central nervous system.[2]
- electrons donated by NADPH.
biliverdin reductase biliverdin ------------------> bilirubin + NADP+ + NADPH + H+
More general terms
More specific terms
- biliverdin reductase A, adult (BLVRA, biliverdin IX-alpha reductase)
- biliverdin reductase B, fetal (BLVRB, biliverdin IX beta-reductase, NADPH-flavin reductase, FLR, BVR-B, biliverdin-IX beta-reductase, green heme-binding protein, GHBP, BLVRB, FLR)
Additional terms
References
- ↑ OMIM https://mirror.omim.org/entry/109750
- ↑ 2.0 2.1 Sedlak TW, Snyder SH. Messenger molecules and cell death: therapeutic implications. JAMA. 2006 Jan 4;295(1):81-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16391220