tyrosine kinase TYK2 (TYK2)

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Function

Structure

Expression

Pathology

  • causes excess tau production

Pharmacology

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P29597.html
  2. Ihle JN et al Signaling by the cytokine receptor superfamily: JAKs and STATs TIBS 19:222 1994 PMID: https://www.ncbi.nlm.nih.gov/pubmed/8048164
  3. Kim J, Tadros B, Liang YH et al TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model. Nat Neurosci. 2024 Dec;27(12):2417-2429. PMID: https://www.ncbi.nlm.nih.gov/pubmed/39528671 PMCID: PMC11614740 Free PMC article.

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