ephB receptor

Function

• selectively activated by ephrin-B ligands
• binding of ephrin B results in phosphorylation of cytoplasmic Tyr(s) in both the ephB receptor & ephrin B; this serves as a bidirectional signal between presynaptic & postsynaptic terminals
• activation of the EphB receptor potentiates glutamate- induced Ca+2 influx through the NMDA receptor

More general terms

• eph family receptor

More specific terms

• ephB5 receptor
• ephrin type-B receptor 1; tyrosine-protein kinase receptor EPH-2; NET; HEK6; ELK (EPHB1, EPHT2, NET)
• Ephrin type-B receptor 2; tyrosine-protein kinase receptor EPH-3; DRT; receptor protein-tyrosine kinase HEK5; ERK; tyrosine-protein kinase TYRO5; renal carcinoma antigen NY-REN-47 (EPHB2; DRT; EPHT3; EPTH3; ERK; HEK5; TYRO5)
• Ephrin type-B receptor 3; tyrosine-protein kinase receptor HEK-2; tyrosine-protein kinase TYRO6 (EPHB3, ETK2, HEK2, TYRO6)
• Ephrin type-B receptor 4; hepatoma transmembrane kinase; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase TYRO11 (EPHB4, HTK, TYRO11)
• ephrin type-B receptor 6; tyrosine-protein kinase-defective receptor EPH-6; HEP (EPHB6)

Additional terms

• ephrin B or ephrin B ligand