ephrin type-B receptor 6; tyrosine-protein kinase-defective receptor EPH-6; HEP (EPHB6)

Function

• kinase-defective receptor for members of the ephrin-B family

Structure

• protein kinase domain is predicted to be catalytically inactive
• belongs to the protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
• contains 2 fibronectin F3 modules
• contains 1 protein kinase domain
• contains 1 SAM (sterile alpha motif) domain

Compartment

membrane

Expression

• strong expression in the brain & pancreas
• weak expression in other tissues, including heart, placenta, lung, liver, skeletal muscle & kidney

More general terms

• ephB receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2051
• OMIM: https://mirror.omim.org/entry/602757
• OMIM: https://mirror.omim.org/entry/602757
• UniProt: http://www.uniprot.org/uniprot/O15197.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2051