MBD2-interacting zinc finger protein; methyl-CpG-binding protein 2-interacting zinc finger protein (MIZF, HINFP)

Introduction

Fucntion:

• transcriptional repressor
• binds to the consensus sequence 5'-CGGACGTT-3' & to the RB1 promoter
• binds MBD2 & a histone deacetylase complex

Structure

• contains 8 C2H2-type zinc fingers

Compartment

nucleus

Expression

• ubiquitous
• highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta, liver

More general terms

• C2H2 type zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/607099
• UniProt: http://www.uniprot.org/uniprot/Q9BQA5.html