C-C chemokine receptor type 8; C-C CKR-8; CC-CKR-8; CCR-8; GPR-CY6; GPRCY6; chemokine receptor-like 1; CKR-L1; TER1; CMKBRL2; CC-chemokine receptor CHEMR1; CDw198 (CCR8, CKRL1, CMKBR8, CMKBRL2)
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Function
- receptor for the chemokine SCYA1/I-309
- may regulate monocyte chemotaxis & thymic cell line apoptosis
- alternative coreceptor with CD4 for HIV-1 infection
Structure
belongs to the G-protein coupled receptor 1 family
Compartment
Notes
originally thought to be a receptor for SCYA3 & SCYA17[3]
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P51685.html
- ↑ Wikipedia; CC chemokine receptors entry http://en.wikipedia.org/wiki/CC_chemokine_receptors
- ↑ 3.0 3.1 Bernardini G et al Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. Eur J Immunol. 1998 Feb;28(2):582-8 PMID: https://www.ncbi.nlm.nih.gov/pubmed/9521068