ephrin type-A receptor 10; ephA10 receptor (EPHA10)

Function

• receptor for members of the ephrin-A family
• binds to EFNA3, EFNA4, EFNA5
• receptor tyrosine kinase catalytically inactive (putative)

Structure

• protein kinase domain is predicted to be catalytically inactive
• belongs to the protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
• contains 2 fibronectin F3 modules
• contains 1 protein kinase domain
• contains 1 SAM (sterile alpha motif) domain

Compartment

• isoforms 1,3: cell membrane
• isoform 2: secreted

Alternative splicing

named isoforms=3

Expression

mainly expressed in testis

More general terms

• ephA receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2846
• OMIM: https://mirror.omim.org/entry/611123
• UniProt: http://www.uniprot.org/uniprot/Q5JZY3.html