ephrin A or ephrin A ligand
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Function
- glypiated ligands for ephA receptors
- ephrin A ligands participate in signal transduction influencing actin cytoskeletal changes, attachment & migration
Compartment
- ephrin A ligands have been localized to lipid rafts which contain other signaling molecules such as G proteins
- in neurons, ephrin A is localizes to presynaptic (axon terminal) sites
More general terms
More specific terms
- ephrin-A1; EPH-related receptor tyrosine kinase ligand 1; LERK-1; immediate early response protein B61; tumor necrosis factor, alpha-induced protein 4 (EFNA1, EPLG1, LERK1, TNFAIP4)
- ephrin-A2; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-L (EFNA2, EPLG6, LERK6)
- ephrin-A3; EPH-related receptor tyrosine kinase ligand 3; LERK-3; EHK1 ligand; EHK1-L; EFL-2 (EFNA3, EFL2, EPLG3, LERK3)
- ephrin-A4; EPH-related receptor tyrosine kinase ligand 4; LERK-4 (EFNA4 EPLG4 LERK4)
- ephrin-A5; EPH-related receptor tyrosine kinase ligand 7; LERK-7; AL-1 (EFNA5, EPLG7, LERK7)
Additional terms
References
- ↑ Eph Nomenclature Committee. Cell 90:403-4 1997
- ↑ Ghosh A. Neurobiology. Learning more about NMDA receptor regulation. Science. 2002 Jan 18;295(5554):449-51. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11799227
- ↑ Cheng N, Brantley DM, Chen J. The ephrins and Eph receptors in angiogenesis. Cytokine Growth Factor Rev. 2002 Feb;13(1):75-85. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11750881