ephrin-A4; EPH-related receptor tyrosine kinase ligand 4; LERK-4 (EFNA4 EPLG4 LERK4)

Function

• may play a role in the interaction between activated B-cells & dendritic cells in tonsils

Structure

• belongs to the ephrin family

Compartment

• isoform 1: cell membrane; lipid-anchor, GPI-anchor
• isoform 2: secreted (probable)

Alternative splicing

named isoforms=2; GPI-anchored form

Expression

• expressed in the adult spleen, lymph node, prostate, ovary, small intestine, & colon, & in fetal heart, lung, liver & kidney
• also detected in hematopoietic cell lines

More general terms

• ephrin A or ephrin A ligand

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1945
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1945
• OMIM: https://mirror.omim.org/entry/601380
• UniProt: http://www.uniprot.org/uniprot/P52798.html