Ephrin type-A receptor 7; ephA7 receptor; tyrosine-protein kinase receptor EHK-3; EPH homology kinase 3; receptor protein-tyrosine kinase HEK11 (EPHA7, EHK3, HEK11, CEK11, MDK1, EBK)

Function

• receptor for members of the ephrin-A family
• binds to ephrin-A1, -A2, -A3, -A4 & -A5
• interacts with PRKCABP & GRIP1 (putative)

Structure

• belongs to the protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
• contains 2 fibronectin F3 modules
• contains 1 protein kinase domain
• contains 1 SAM (sterile alpha motif) domain

Compartment

membrane

Alternative splicing

named isoforms=3

Expression

widely expressed

More general terms

• ephA receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2045
• OMIM: https://mirror.omim.org/entry/602190
• UniProt: http://www.uniprot.org/uniprot/Q15375.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2045