Ephrin type-A receptor 5; tyrosine-protein kinase receptor EHK-1; EPH homology kinase 1; receptor protein-tyrosine kinase HEK7 (EPHA5, EHK1, HEK7)

Function

• receptor for members of the ephrin-A family
• binds to ephrin-A1, ephrin-A2, ephrin-A3, ephrin-A4, ephrin-A5

Structure

• belongs to the protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
• contains 2 fibronectin F3 modules
• contains 1 protein kinase domain
• contains 1 SAM (sterile alpha motif) domain

Compartment

membrane

Alternative splicing

named isoforms=2

Expression

almost exclusively expressed in nervous system

More general terms

• ephA receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2044
• OMIM: https://mirror.omim.org/entry/600004
• UniProt: http://www.uniprot.org/uniprot/P54756.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2044