dumping syndrome; postgastrectomy syndrome; rapid gastric emptying
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Etiology
- gastrectomy with or without vagotomy
- rapid gastric emptying of a large osmotic load into the small intestine
Clinical manifestations
- abdominal discomfort, diarrhea, nausea/vomiting, bloating & borborygmi
- early dumping occurs ~15-30 minutes after eating
- vasomotor manifestations occur later within 60-90 minutes
- late dumping occurs 1-3 hours after eating[2]
- reactive hypoglycemia
- inability to concentration, altered consciousness, faintness
Management
- 6 small meals/day, high in protein, low in refined carbohydrates
- avoid liquid with meals, take liquids following meals[2]
- pectin
- anticholinergic agents
- ephedrine
- subcutaneous octreotide in refractory cases
More general terms
References
- ↑ Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 344
- ↑ 2.0 2.1 2.2 2.3 Medical Knowledge Self Assessment Program (MKSAP) 14, 18, 19. American College of Physicians, Philadelphia 2006, 2018, 2021.
Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022 - ↑ Berg P, McCallum R. Dumping Syndrome: A Review of the Current Concepts of Pathophysiology, Diagnosis, and Treatment. Dig Dis Sci. 2016 Jan;61(1):11-8. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26396002
- ↑ Dumping Syndrome https://www.niddk.nih.gov/health-information/digestive-diseases/dumping-syndrome