age-associated changes in hearing
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Introduction
Hearing undergoes change with aging.
Physiology
- degenerative changes of ossicle
- decreased elasticity & efficiency of ossicle articulation[5]
- increased obstruction of eustachian tube
- thickening of tympanic membrane[5]
- conductive hearing loss (low-frequency range)[5]
- described as decreased efficiency of ossicular articulations[5]
- exacerbation by otosclerosis
- decreased perception of high frequency sound (presbycusis) narrowing the range of auditory frequency responsiveness
- decrease in cochlear neurons in the spiral ganglion
- loss of hair cells in the organ of Corti[6]
- patchy atrophy of the stria vascularis
- changes in cochlear duct[5]
- decreased pitch discrimination
- difficulty in discrimating source of sound
- impaired discrimination of target from noise
- central processing deficit
- the external auditory canal progressively narrows[5]
More general terms
Additional terms
References
- ↑ Essentials of Clinical Geriatrics, 4th ed, Kane RL et al (eds) McGraw Hill, NY, 1999
- ↑ UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 29-Oct 2, 2004
- ↑ The Merck Manual of Geriatrics, 3rdh ed, Merck & Co, Rahway NJ, 2000
- ↑ Taffet GE, Physiology of Aging, In: Geriatric Medicine: An Evidence-Based Approach, 4th ed, Cassel CK et al (eds), Springer-Verlag, New York, 2003
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022 - ↑ 6.0 6.1 Komaroff AL NEJM Journal Watch. March 23, 2017 Massachusetts Medical Society (subscription needed) http://www.jwatch.org
McLean WJ, Yin X, Lu L et al. Clonal expansion of Lgr5-positive cells from mammalian cochlea and high-purity generation of sensory hair cells. Cell Reports 2017 Feb 21; 18:1917 PMID: https://www.ncbi.nlm.nih.gov/pubmed/28228258 Free Article - ↑ Fischer N, Chacko JL, Glueckert R et al. Age-dependent changes in the cochlea. Gerontology. 2020;66(1):33-39 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31117093 https://www.karger.com/Article/Abstract/499582
- ↑ Keithley EM. Pathology and mechanism of cochlear aging. J Neurosci Res. 2020;98(9):1674-1684 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31066107 PMCID: PMC7496655 Free PMC article https://onlinelibrary.wiley.com/doi/10.1002/jnr.24439