sulopenem etzadroxil

Indications

• in combination with probenecid to treat uncomplicated urinary tract infections due to certain bacteria in women with limited or no alternative oral antibacterial treatment options

Contraindications

• blood dyscrasias
• uric acid kidney stones

Dosage

oral twice daily for 5 days

Antimicrobial activity

• Escherichia coli
• Klebsiella pneumoniae
• Proteus mirabilis

Adverse effects

• diarrhea, nausea/vomiting, vulvovaginal yease infection, headache
• Clostridioides difficile colitis

Drug interactions

• ketorolac tromethamine

• drug interaction(s) anticonvulsants with anti-bacterial agents
• drug interaction(s) of antibiotics with warfarin

More general terms

• carbapenem (thienamycin)

Component of

• probenecid/sulopenem etzadroxil

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9950244
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=23642298