probenecid/sulopenem etzadroxil

Indications

• sulopenem etzadroxil in combination with probenecid to treat uncomplicated urinary tract infections due to certain bacteria in women with limited or no alternative oral antibacterial

Contraindications

• blood dyscrasias
• uric acid kidney stones

Dosage

oral twice daily for 5 days

Antimicrobial activity

• Escherichia coli
• Klebsiella pneumoniae
• Proteus mirabilis

Adverse effects

• diarrhea, nausea/vomiting, vulvovaginal yease infection, headache
• Clostridioides difficile colitis

Drug interactions

• ketorolac tromethamine

More general terms

• pharmacologic combination

Components

• probenecid (Benemid, Probalan)
• sulopenem etzadroxil