SARS CoV2 & pregnancy & breastfeeding

^[1]^[2]^[3]

Laboratory

maternal IgG antibodies to SARS-CoV2 are transferred across the placenta after asymptomatic as well as symptomatic infection during pregnancy^[1]
cord blood antibody concentrations correlated with maternal antibody concentrations & with duration between onset of infection & delivery
SARS-CoV2 specific IgA & IgG antibodies found in breast milk for at least 6 weeks after COVID-19 vaccination^[3]
- IgA secretion found as early as 2 weeks after vaccination, IgG after 4 weeks (a week after the second Pfizer vaccine)

↑ ^1.0 ^1.1 Flannery DD, Gouma S, Dhudasia MD et al Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios. JAMA Pediatr. Published online January 29, 2021 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33512440 PMCID: PMC7846944 (available on 2022-01-29) https://jamanetwork.com/journals/jamapediatrics/fullarticle/2775945
Munoz FM Can We Protect Pregnant Women and Young Infants From COVID-19 Through Maternal Immunization? JAMA Pediatr. Published online January 29, 2021 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33512398 https://jamanetwork.com/journals/jamapediatrics/fullarticle/2775944
↑ ^2.0 ^2.1 Shimabukuro TT, Kim SY, Myers TR et al Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons. N Engl J Med. 2021. April 21. PMID: https://www.ncbi.nlm.nih.gov/pubmed/33882218 https://www.nejm.org/doi/full/10.1056/NEJMoa2104983
↑ ^3.0 ^3.1 Perl SH, Uzan-Yulzari A, Klainer H et al SARS-CoV-2-Specific Antibodies in Breast Milk After COVID-19 Vaccination of Breastfeeding Women. JAMA. 2021;325(19):2013-2014 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33843975 PMCID: PMC8042567 (available on 2021-10-12) https://jamanetwork.com/journals/jama/fullarticle/2778766